Cargando…
Novel Common Integration Sites Targeted by Mouse Mammary Tumor Virus Insertion in Mammary Tumors Have Oncogenic Activity
Non-acute transforming retroviruses like mouse mammary tumor virus (MMTV) cause cancer, at least in part, through integration near cellular genes involved in growth control, thereby de-regulating their expression. It is well-established that MMTV commonly integrates near and activates expression of...
Autores principales: | Kim, Hyoung H., van den Heuvel, A. Pieter J., Schmidt, John W., Ross, Susan R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210173/ https://www.ncbi.nlm.nih.gov/pubmed/22087314 http://dx.doi.org/10.1371/journal.pone.0027425 |
Ejemplares similares
-
Genes affected by mouse mammary tumor virus (MMTV) proviral insertions in mouse mammary tumors are deregulated or mutated in primary human mammary tumors
por: Callahan, Robert, et al.
Publicado: (2012) -
Mouse Mammary Tumor Virus Molecular Biology and Oncogenesis
por: Ross, Susan R.
Publicado: (2010) -
Jnk2 Effects on Tumor Development, Genetic Instability and Replicative Stress in an Oncogene-Driven Mouse Mammary Tumor Model
por: Chen, Peila, et al.
Publicado: (2010) -
Late developing mammary tumors and hyperplasia induced by a low-oncogenic variant of mouse mammary tumor virus (MMTV) express genes identical to those induced by canonical MMTV
por: Bruno, Robert D, et al.
Publicado: (2013) -
Cross-species oncogenic signatures of breast cancer in canine mammary tumors
por: Kim, Tae-Min, et al.
Publicado: (2020)