Dissociation of Bone Resorption and Bone Formation in Adult Mice with a Non-Functional V-ATPase in Osteoclasts Leads to Increased Bone Strength

Osteopetrosis caused by defective acid secretion by the osteoclast, is characterized by defective bone resorption, increased osteoclast numbers, while bone formation is normal or increased. In contrast the bones are of poor quality, despite this uncoupling of formation from resorption. To shed light...

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Detalles Bibliográficos
Autores principales: Henriksen, Kim, Flores, Carmen, Thomsen, Jesper S., Brüel, Anne-Marie, Thudium, Christian S., Neutzsky-Wulff, Anita V., Langenbach, Geerling E. J., Sims, Natalie, Askmyr, Maria, Martin, Thomas J., Everts, Vincent, Karsdal, Morten A., Richter, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210177/
https://www.ncbi.nlm.nih.gov/pubmed/22087326
http://dx.doi.org/10.1371/journal.pone.0027482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210177/
https://www.ncbi.nlm.nih.gov/pubmed/22087326
http://dx.doi.org/10.1371/journal.pone.0027482

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