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Peptides from aminoacyl-tRNA synthetases can cure the defects due to mutations in mt tRNA genes

Recent results from several laboratories have confirmed that human and yeast leucyl- and valyl-tRNA synthetases can rescue the respiratory defects due to mutations in mitochondrial tRNA genes. In this report we show that this effect cannot be ascribed to the catalytic activity per se and that isolat...

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Detalles Bibliográficos
Autores principales: Francisci, Silvia, Montanari, Arianna, De Luca, Cristina, Frontali, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210327/
https://www.ncbi.nlm.nih.gov/pubmed/21903180
http://dx.doi.org/10.1016/j.mito.2011.08.006