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Tfam, a mitochondrial transcription and packaging factor, imposes a U-turn on mitochondrial DNA
Tfam, a DNA binding protein with tandem HMG (high mobility group)-box domains, plays a central role in expression, maintenance, and organization of the mitochondrial genome. It activates transcription from mitochondrial promoters and organizes the mitochondrial genome into nucleoids. Using X-ray cry...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210390/ https://www.ncbi.nlm.nih.gov/pubmed/22037171 http://dx.doi.org/10.1038/nsmb.2159 |