Initiation Factor eIF2γ Promotes eIF2–GTP–Met-tRNA(i)(Met) Ternary Complex Binding to the 40S Ribosome

In contrast to elongation factor EF-Tu, which delivers aminoacyl-tRNAs to the ribosomal A-site, eukaryotic initiation factor eIF2 binds initiator Met-tRNA(i)(Met) to the P-site of the 40S ribosomal subunit. We used directed hydroxyl radical probing experiments to map the binding of Saccharomyces cer...

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Detalles Bibliográficos
Autores principales: Shin, Byung-Sik, Kim, Joo-Ran, Walker, Sarah E., Dong, Jinsheng, Lorsch, Jon R., Dever, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210414/
https://www.ncbi.nlm.nih.gov/pubmed/22002225
http://dx.doi.org/10.1038/nsmb.2133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210414/
https://www.ncbi.nlm.nih.gov/pubmed/22002225
http://dx.doi.org/10.1038/nsmb.2133

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