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Prospective Power Calculations for the Four Lab Study of A Multigenerational Reproductive/Developmental Toxicity Rodent Bioassay Using A Complex Mixture of Disinfection By-Products in the Low-Response Region

In complex mixture toxicology, there is growing emphasis on testing environmentally representative doses that improve the relevance of results for health risk assessment, but are typically much lower than those used in traditional toxicology studies. Traditional experimental designs with typical sam...

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Detalles Bibliográficos
Autores principales: Dingus, Cheryl A., Teuschler, Linda K., Rice, Glenn E., Simmons, Jane Ellen, Narotsky, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210599/
https://www.ncbi.nlm.nih.gov/pubmed/22073030
http://dx.doi.org/10.3390/ijerph8104082