Prolyl Hydroxylase PHD3 Enhances the Hypoxic Survival and G1 to S Transition of Carcinoma Cells

Hypoxia restricts cell proliferation and cell cycle progression at the G1/S interface but at least a subpopulation of carcinoma cells can escape the restriction. In carcinoma hypoxia may in fact select for cells with enhanced hypoxic survival and increased aggressiveness. The cellular oxygen sensors...

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Detalles Bibliográficos
Autores principales: Högel, Heidi, Rantanen, Krista, Jokilehto, Terhi, Grenman, Reidar, Jaakkola, Panu M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210766/
https://www.ncbi.nlm.nih.gov/pubmed/22087251
http://dx.doi.org/10.1371/journal.pone.0027112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210766/
https://www.ncbi.nlm.nih.gov/pubmed/22087251
http://dx.doi.org/10.1371/journal.pone.0027112

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