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Evolutionarily Conserved Linkage between Enzyme Fold, Flexibility, and Catalysis
Proteins are intrinsically flexible molecules. The role of internal motions in a protein's designated function is widely debated. The role of protein structure in enzyme catalysis is well established, and conservation of structural features provides vital clues to their role in function. Recent...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210774/ https://www.ncbi.nlm.nih.gov/pubmed/22087074 http://dx.doi.org/10.1371/journal.pbio.1001193 |