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High Glucose Promotes Pancreatic Cancer Cell Proliferation via the Induction of EGF Expression and Transactivation of EGFR

Multiple lines of evidence suggest that a large portion of pancreatic cancer patients suffer from either hyperglycemia or diabetes, both of which are characterized by high blood glucose level. However, the underlying biological mechanism of this phenomenon is largely unknown. In the present study, w...

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Detalles Bibliográficos
Autores principales: Han, Liang, Ma, Qingyong, Li, Junhui, Liu, Han, Li, Wei, Ma, Guodong, Xu, Qinhong, Zhou, Shuang, Wu, Erxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210779/
https://www.ncbi.nlm.nih.gov/pubmed/22087246
http://dx.doi.org/10.1371/journal.pone.0027074