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Computational Modeling of Interactions between Multiple Myeloma and the Bone Microenvironment
Multiple Myeloma (MM) is a B-cell malignancy that is characterized by osteolytic bone lesions. It has been postulated that positive feedback loops in the interactions between MM cells and the bone microenvironment form reinforcing ‘vicious cycles’, resulting in more bone resorption and MM cell popul...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210790/ https://www.ncbi.nlm.nih.gov/pubmed/22110661 http://dx.doi.org/10.1371/journal.pone.0027494 |