Computational Modeling of Interactions between Multiple Myeloma and the Bone Microenvironment

Multiple Myeloma (MM) is a B-cell malignancy that is characterized by osteolytic bone lesions. It has been postulated that positive feedback loops in the interactions between MM cells and the bone microenvironment form reinforcing ‘vicious cycles’, resulting in more bone resorption and MM cell popul...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Pivonka, Peter, Buenzli, Pascal R., Smith, David W., Dunstan, Colin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210790/
https://www.ncbi.nlm.nih.gov/pubmed/22110661
http://dx.doi.org/10.1371/journal.pone.0027494

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