Regulation of Interleukin-10 Receptor Ubiquitination and Stability by Beta-TrCP-Containing Ubiquitin E3 Ligase

Interleukin-10 (IL-10) initiates potent anti-inflammatory effects via activating its cell surface receptor, composed of IL-10R1 and IL-10R2 subunits. The level of IL-10R1 is a major determinant of the cells' responsiveness to IL-10. Here, via a series of biochemical analyses using 293T cells re...

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Detalles Bibliográficos
Autores principales: Jiang, Hui, Lu, Yi, Yuan, Liang, Liu, Jianghuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210801/
https://www.ncbi.nlm.nih.gov/pubmed/22087322
http://dx.doi.org/10.1371/journal.pone.0027464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210801/
https://www.ncbi.nlm.nih.gov/pubmed/22087322
http://dx.doi.org/10.1371/journal.pone.0027464

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