CARD8 and NLRP1 Undergo Autoproteolytic Processing through a ZU5-Like Domain

The “Function to Find Domain” (FIIND)-containing proteins CARD8 (Cardinal; Tucan) and NLRP1 (NALP1; NAC) are well known components of inflammasomes, multiprotein complexes responsible for activation of caspase-1, a regulator of inflammation and innate immunity. Although identified many years ago, th...

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Detalles Bibliográficos
Autores principales: D'Osualdo, Andrea, Weichenberger, Christian X., Wagner, Roland N., Godzik, Adam, Wooley, John, Reed, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210808/
https://www.ncbi.nlm.nih.gov/pubmed/22087307
http://dx.doi.org/10.1371/journal.pone.0027396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210808/
https://www.ncbi.nlm.nih.gov/pubmed/22087307
http://dx.doi.org/10.1371/journal.pone.0027396

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