Cargando…

Versatile Roles of V-ATPases Accessory Subunit Ac45 in Osteoclast Formation and Function

Vacuolar-type H(+)-ATPases (V-ATPases) are macromolecular proton pumps that acidify intracellular cargos and deliver protons across the plasma membrane of a variety of specialized cells, including bone-resorbing osteoclasts. Extracellular acidification is crucial for osteoclastic bone resorption, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Qin, An, Cheng, Tak S., Lin, Zhen, Pavlos, Nathan J., Jiang, Qing, Xu, Jiake, Dai, Ke R., Zheng, Ming H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210823/
https://www.ncbi.nlm.nih.gov/pubmed/22087256
http://dx.doi.org/10.1371/journal.pone.0027155