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Versatile Roles of V-ATPases Accessory Subunit Ac45 in Osteoclast Formation and Function
Vacuolar-type H(+)-ATPases (V-ATPases) are macromolecular proton pumps that acidify intracellular cargos and deliver protons across the plasma membrane of a variety of specialized cells, including bone-resorbing osteoclasts. Extracellular acidification is crucial for osteoclastic bone resorption, a...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210823/ https://www.ncbi.nlm.nih.gov/pubmed/22087256 http://dx.doi.org/10.1371/journal.pone.0027155 |