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Epigenetic suppression of GAD65 expression mediates persistent pain

Chronic pain is a common neurological disease involving lasting, multifaceted maladaptations from gene modulations to synaptic malfunctions and to emotional disorders. Sustained pathological stimuli in many diseases alter output activities of certain genes through epigenetic modifications, but it is...

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Detalles Bibliográficos
Autores principales: Zhang, Zhi, Cai, Youqing, Zou, Fang, Bie, Bihua, Pan, Zhizhong Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210928/
https://www.ncbi.nlm.nih.gov/pubmed/21983856
http://dx.doi.org/10.1038/nm.2442