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Structural Determinants of CX-4945 Derivatives as Protein Kinase CK2 Inhibitors: A Computational Study

Protein kinase CK2, also known as casein kinase-2, is involved in a broad range of physiological events including cell growth, proliferation and suppression of apoptosis which are related to human cancers. A series of compounds were identified as CK2 inhibitors and their inhibitory activities varied...

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Detalles Bibliográficos
Autores principales: Liu, Hongbo, Wang, Xia, Wang, Jian, Wang, Jinghui, Li, Yan, Yang, Ling, Li, Guohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211023/
https://www.ncbi.nlm.nih.gov/pubmed/22072932
http://dx.doi.org/10.3390/ijms12107004