Comparative Molecular Field Analysis (CoMFA) and Comparative Molecular Similarity Indices Analysis (CoMSIA) Studies on α(1A)-Adrenergic Receptor Antagonists Based on Pharmacophore Molecular Alignment

The α(1A)-adrenergic receptor (α(1A)-AR) antagonist is useful in treating benign prostatic hyperplasia, lower urinary tract symptoms, and cardiac arrhythmia. Three-dimensional quantitative structure-activity relationship (3D-QSAR) studies were performed on a set of α(1A)-AR antagonists of N-aryl and...

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Detalles Bibliográficos
Autores principales: Zhao, Xin, Chen, Minsheng, Huang, Biyun, Ji, Hong, Yuan, Mu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211024/
https://www.ncbi.nlm.nih.gov/pubmed/22072933
http://dx.doi.org/10.3390/ijms12107022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211024/
https://www.ncbi.nlm.nih.gov/pubmed/22072933
http://dx.doi.org/10.3390/ijms12107022

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