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Intestine-Specific, Oral Delivery of Captopril/Montmorillonite: Formulation and Release Kinetics

The intercalation of captopril (CP) into the interlayers of montmorillonite (MMT) affords an intestine-selective drug delivery system that has a captopril-loading capacity of up to ca. 14 %w/w and which exhibits near-zero-order release kinetics.

Detalles Bibliográficos
Autores principales: Madurai, Suguna Lakshmi, Joseph, Stella Winnarasi, Mandal, Asit Baran, Tsibouklis, John, Reddy, Boreddy SR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211200/
https://www.ncbi.nlm.nih.gov/pubmed/27502639
http://dx.doi.org/10.1007/s11671-010-9749-0