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Preparation and evaluation of novel mixed micelles as nanocarriers for intravenous delivery of propofol

Novel mixed polymeric micelles formed from biocompatible polymers, poly(ethylene glycol)-poly(lactide) (mPEG-PLA) and polyoxyethylene-660-12-hydroxy stearate (Solutol HS15), were fabricated and used as a nanocarrier for solubilizing poorly soluble anesthetic drug propofol. The solubilization of prop...

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Detalles Bibliográficos
Autores principales: Li, Xinru, Zhang, Yanhui, Fan, Yating, Zhou, Yanxia, Wang, Xiaoning, Fan, Chao, Liu, Yan, Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211339/
https://www.ncbi.nlm.nih.gov/pubmed/21711808
http://dx.doi.org/10.1186/1556-276X-6-275