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High-resolution structure of a retroviral protease folded as a monomer

Mason–Pfizer monkey virus (M-PMV), a D-type retrovirus assembling in the cytoplasm, causes simian acquired immuno­deficiency syndrome (SAIDS) in rhesus monkeys. Its pepsin-like aspartic protease (retropepsin) is an integral part of the expressed retroviral polyproteins. As in all retroviral life cyc...

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Detalles Bibliográficos
Autores principales: Gilski, Miroslaw, Kazmierczyk, Maciej, Krzywda, Szymon, Zábranská, Helena, Cooper, Seth, Popović, Zoran, Khatib, Firas, DiMaio, Frank, Thompson, James, Baker, David, Pichová, Iva, Jaskolski, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211970/
https://www.ncbi.nlm.nih.gov/pubmed/22101816
http://dx.doi.org/10.1107/S0907444911035943