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Mutagen-Specific Mutation Signature Determines Global microRNA Binding

Micro-RNAs (miRNAs) are small non-coding RNAs that regulate gene products at the post-transcriptional level. It is thought that loss of cell regulation by miRNAs supports cancer development. Based on whole genome sequencing of a melanoma tumor, we predict, using three different computational algorit...

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Detalles Bibliográficos
Autores principales: Greenberg, Eyal, Rechavi, Gideon, Amariglio, Ninette, Solomon, Oz, Schachter, Jacob, Markel, Gal, Eyal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212558/
https://www.ncbi.nlm.nih.gov/pubmed/22096567
http://dx.doi.org/10.1371/journal.pone.0027400