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Average Rank-Based Score to Measure Deregulation of Molecular Pathway Gene Sets

BACKGROUND: Deregulation of biological pathways has been shown to be involved in the turmorigenesis of a variety of cancers. The co-regulation of pathways in tumor and normal tissues has not been studied in a systematic manner. RESULTS: In this study we propose a novel statistic named AR-score (aver...

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Detalles Bibliográficos
Autores principales: Yang, Huan, Cheng, Chao, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212578/
https://www.ncbi.nlm.nih.gov/pubmed/22096597
http://dx.doi.org/10.1371/journal.pone.0027579