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Average Rank-Based Score to Measure Deregulation of Molecular Pathway Gene Sets
BACKGROUND: Deregulation of biological pathways has been shown to be involved in the turmorigenesis of a variety of cancers. The co-regulation of pathways in tumor and normal tissues has not been studied in a systematic manner. RESULTS: In this study we propose a novel statistic named AR-score (aver...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212578/ https://www.ncbi.nlm.nih.gov/pubmed/22096597 http://dx.doi.org/10.1371/journal.pone.0027579 |