Structural neuroanatomy of face processing in frontotemporal lobar degeneration

Impairments of face processing occur frequently in frontotemporal lobar degeneration (FTLD) but the neuroanatomical basis for these deficits has seldom been studied systematically. Here a prospective voxel based morphometry study is described addressing the neuroanatomy of two key dimensions of face...

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Autores principales: Omar, Rohani, Rohrer, Jonathan D, Hailstone, Julia C, Warren, Jason D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212647/
https://www.ncbi.nlm.nih.gov/pubmed/21172863
http://dx.doi.org/10.1136/jnnp.2010.227983
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author Omar, Rohani
Rohrer, Jonathan D
Hailstone, Julia C
Warren, Jason D
author_facet Omar, Rohani
Rohrer, Jonathan D
Hailstone, Julia C
Warren, Jason D
author_sort Omar, Rohani
collection PubMed
description Impairments of face processing occur frequently in frontotemporal lobar degeneration (FTLD) but the neuroanatomical basis for these deficits has seldom been studied systematically. Here a prospective voxel based morphometry study is described addressing the neuroanatomy of two key dimensions of face processing—face identification and facial emotion recognition—in a single cohort of 32 patients with FTLD (19 with frontal variant and 13 with temporal variant FTLD). For the FTLD group as a whole, face identification was positively associated with grey matter in the right anterior fusiform gyrus while recognition of angry expressions was positively associated with grey matter in the bilateral insula cortex. FTLD provides a perspective on the neuroanatomy of face processing that is complementary to focal lesion and normal functional imaging work.
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spelling pubmed-32126472011-11-14 Structural neuroanatomy of face processing in frontotemporal lobar degeneration Omar, Rohani Rohrer, Jonathan D Hailstone, Julia C Warren, Jason D J Neurol Neurosurg Psychiatry Short Report Impairments of face processing occur frequently in frontotemporal lobar degeneration (FTLD) but the neuroanatomical basis for these deficits has seldom been studied systematically. Here a prospective voxel based morphometry study is described addressing the neuroanatomy of two key dimensions of face processing—face identification and facial emotion recognition—in a single cohort of 32 patients with FTLD (19 with frontal variant and 13 with temporal variant FTLD). For the FTLD group as a whole, face identification was positively associated with grey matter in the right anterior fusiform gyrus while recognition of angry expressions was positively associated with grey matter in the bilateral insula cortex. FTLD provides a perspective on the neuroanatomy of face processing that is complementary to focal lesion and normal functional imaging work. BMJ Group 2010-12-16 2011-12 /pmc/articles/PMC3212647/ /pubmed/21172863 http://dx.doi.org/10.1136/jnnp.2010.227983 Text en © 2011, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode.
spellingShingle Short Report
Omar, Rohani
Rohrer, Jonathan D
Hailstone, Julia C
Warren, Jason D
Structural neuroanatomy of face processing in frontotemporal lobar degeneration
title Structural neuroanatomy of face processing in frontotemporal lobar degeneration
title_full Structural neuroanatomy of face processing in frontotemporal lobar degeneration
title_fullStr Structural neuroanatomy of face processing in frontotemporal lobar degeneration
title_full_unstemmed Structural neuroanatomy of face processing in frontotemporal lobar degeneration
title_short Structural neuroanatomy of face processing in frontotemporal lobar degeneration
title_sort structural neuroanatomy of face processing in frontotemporal lobar degeneration
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212647/
https://www.ncbi.nlm.nih.gov/pubmed/21172863
http://dx.doi.org/10.1136/jnnp.2010.227983
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