V(D)J-mediated Translocations in Lymphoid Neoplasms: A Functional Assessment of Genomic Instability by Cryptic Sites

Most lymphoid malignancies are initiated by specific chromosomal translocations between immunoglobulin (Ig)/T cell receptor (TCR) gene segments and cellular proto-oncogenes. In many cases, illegitimate V(D)J recombination has been proposed to be involved in the translocation process, but this has ne...

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Detalles Bibliográficos
Autores principales: Marculescu, Rodrig, Le, Trang, Simon, Paul, Jaeger, Ulrich, Nadel, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212722/
https://www.ncbi.nlm.nih.gov/pubmed/11781368
http://dx.doi.org/10.1084/jem.20011578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212722/
https://www.ncbi.nlm.nih.gov/pubmed/11781368
http://dx.doi.org/10.1084/jem.20011578

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