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Improvement of cardiac contractile function by peptide-based inhibition of NF-κB in the utrophin/dystrophin-deficient murine model of muscular dystrophy

BACKGROUND: Duchenne muscular dystrophy (DMD) is an inherited and progressive disease causing striated muscle deterioration. Patients in their twenties generally die from either respiratory or cardiac failure. In order to improve the lifespan and quality of life of DMD patients, it is important to p...

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Detalles Bibliográficos
Autores principales: Delfín, Dawn A, Xu, Ying, Peterson, Jennifer M, Guttridge, Denis C, Rafael-Fortney, Jill A, Janssen, Paul ML
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212940/
https://www.ncbi.nlm.nih.gov/pubmed/21586145
http://dx.doi.org/10.1186/1479-5876-9-68