Resveratrol inhibits Cdk5 activity through regulation of p35 expression

BACKGROUND: We have previously reported that cyclin-dependent kinase 5 (Cdk5) participates in the regulation of nociceptive signaling. Through activation of the ERK1/2 pathway, Tumor Necrosis Factor-α (TNF-α) induces expression of Egr-1. This results in the sustained and robust expression of p35, a...

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Detalles Bibliográficos
Autores principales: Utreras, Elias, Terse, Anita, Keller, Jason, Iadarola, Michael J, Kulkarni, Ashok B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212955/
https://www.ncbi.nlm.nih.gov/pubmed/21736731
http://dx.doi.org/10.1186/1744-8069-7-49

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212955/
https://www.ncbi.nlm.nih.gov/pubmed/21736731
http://dx.doi.org/10.1186/1744-8069-7-49

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