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An in vitro co-culture model of esophageal cells identifies ascorbic acid as a modulator of cell competition

BACKGROUND: The evolutionary dynamics between interacting heterogeneous cell types are fundamental properties of neoplastic progression but can be difficult to measure and quantify. Cancers are heterogeneous mixtures of mutant clones but the direct effect of interactions between these clones is rare...

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Detalles Bibliográficos
Autores principales: Merlo, Lauren MF, Kosoff, Rachelle E, Gardiner, Kristin L, Maley, Carlo C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213018/
https://www.ncbi.nlm.nih.gov/pubmed/22026449
http://dx.doi.org/10.1186/1471-2407-11-461