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Expression of an IRF-3 fusion protein and mouse estrogen receptor, inhibits hepatitis C viral replication in RIG-I-deficient Huh 7.5 cells

Interferon Regulatory Factor-3 (IRF-3) plays a central role in the induction of interferon (IFN) production and succeeding interferon-stimulated genes (ISG) expression en route for restraining hepatitis C virus (HCV) infection. Here, we established a stable Huh7.5-IRF3ER cell line expressing a fusio...

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Detalles Bibliográficos
Autores principales: Yao, Luyu, Yan, Xiaobo, Dong, Huijia, Nelson, David R, Liu, Chen, Li, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213043/
https://www.ncbi.nlm.nih.gov/pubmed/21936899
http://dx.doi.org/10.1186/1743-422X-8-445