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Expression of an IRF-3 fusion protein and mouse estrogen receptor, inhibits hepatitis C viral replication in RIG-I-deficient Huh 7.5 cells
Interferon Regulatory Factor-3 (IRF-3) plays a central role in the induction of interferon (IFN) production and succeeding interferon-stimulated genes (ISG) expression en route for restraining hepatitis C virus (HCV) infection. Here, we established a stable Huh7.5-IRF3ER cell line expressing a fusio...
Autores principales: | Yao, Luyu, Yan, Xiaobo, Dong, Huijia, Nelson, David R, Liu, Chen, Li, Xiaoyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213043/ https://www.ncbi.nlm.nih.gov/pubmed/21936899 http://dx.doi.org/10.1186/1743-422X-8-445 |
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