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Prolonged-release melatonin versus placebo for benzodiazepine discontinuation in patients with schizophrenia: a randomized clinical trial - the SMART trial protocol

BACKGROUND: Treatment of schizophrenia frequently includes prolonged benzodiazepine administration despite a lack of evidence of its use. It is often difficult to discontinue benzodiazepines because of the development of dependence. We aim to assess if melatonin can facilitate the withdrawal of prol...

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Detalles Bibliográficos
Autores principales: Baandrup, Lone, Fagerlund, Birgitte, Jennum, Poul, Lublin, Henrik, Hansen, Jane L, Winkel, Per, Gluud, Christian, Oranje, Bob, Glenthoj, Birte Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213077/
https://www.ncbi.nlm.nih.gov/pubmed/21975110
http://dx.doi.org/10.1186/1471-244X-11-160