The ATP-binding cassette transporters ABCB1 and ABCC1 are not regulated by hypoxia in immortalised human brain microvascular endothelial cells

BACKGROUND: ATP-binding cassette transporters at the blood-brain barrier are actively regulated upon ischemic stroke in a way that impedes the access of pharmacological compounds to the brain tissue. The luminal endothelial transporter ABCB1 was recently shown to be increased, whereas the abluminal...

Descripción completa

Detalles Bibliográficos
Autores principales: Patak, Pauline, Jin, Fengyan, Schäfer, Simon T, Metzen, Eric, Hermann, Dirk M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213079/
https://www.ncbi.nlm.nih.gov/pubmed/22029974
http://dx.doi.org/10.1186/2040-7378-3-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213079/
https://www.ncbi.nlm.nih.gov/pubmed/22029974
http://dx.doi.org/10.1186/2040-7378-3-12

Ejemplares similares