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The ATP-binding cassette transporters ABCB1 and ABCC1 are not regulated by hypoxia in immortalised human brain microvascular endothelial cells

BACKGROUND: ATP-binding cassette transporters at the blood-brain barrier are actively regulated upon ischemic stroke in a way that impedes the access of pharmacological compounds to the brain tissue. The luminal endothelial transporter ABCB1 was recently shown to be increased, whereas the abluminal...

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Detalles Bibliográficos
Autores principales:	Patak, Pauline, Jin, Fengyan, Schäfer, Simon T, Metzen, Eric, Hermann, Dirk M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213079/ https://www.ncbi.nlm.nih.gov/pubmed/22029974 http://dx.doi.org/10.1186/2040-7378-3-12

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