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Prdm9, a Major Determinant of Meiotic Recombination Hotspots, Is Not Functional in Dogs and Their Wild Relatives, Wolves and Coyotes

Meiotic recombination is a fundamental process needed for the correct segregation of chromosomes during meiosis in sexually reproducing organisms. In humans, 80% of crossovers are estimated to occur at specific areas of the genome called recombination hotspots. Recently, a protein called PRDM9 was i...

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Detalles Bibliográficos
Autores principales: Muñoz-Fuentes, Violeta, Di Rienzo, Anna, Vilà, Carles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213085/
https://www.ncbi.nlm.nih.gov/pubmed/22102853
http://dx.doi.org/10.1371/journal.pone.0025498