Cargando…
Prdm9, a Major Determinant of Meiotic Recombination Hotspots, Is Not Functional in Dogs and Their Wild Relatives, Wolves and Coyotes
Meiotic recombination is a fundamental process needed for the correct segregation of chromosomes during meiosis in sexually reproducing organisms. In humans, 80% of crossovers are estimated to occur at specific areas of the genome called recombination hotspots. Recently, a protein called PRDM9 was i...
Autores principales: | Muñoz-Fuentes, Violeta, Di Rienzo, Anna, Vilà, Carles |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213085/ https://www.ncbi.nlm.nih.gov/pubmed/22102853 http://dx.doi.org/10.1371/journal.pone.0025498 |
Ejemplares similares
-
PRDM9 points the zinc finger at meiotic recombination hotspots
por: Neale, Matthew J
Publicado: (2010) -
ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair
por: Wells, Daniel, et al.
Publicado: (2020) -
The Case of the Fickle Fingers: How the PRDM9 Zinc Finger Protein Specifies Meiotic Recombination Hotspots in Humans
por: Ségurel, Laure, et al.
Publicado: (2011) -
PRDM9 Drives Evolutionary Erosion of Hotspots in Mus musculus through Haplotype-Specific Initiation of Meiotic Recombination
por: Baker, Christopher L., et al.
Publicado: (2015) -
The RNA-binding protein FUS/TLS interacts with SPO11 and PRDM9 and localize at meiotic recombination hotspots
por: Giannattasio, Teresa, et al.
Publicado: (2023)