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Detection of the Onset of Ischemia and Carcinogenesis by Hypoxia-Inducible Transcription Factor-Based In Vivo Bioluminescence Imaging

An animal model for the early detection of common fatal diseases such as ischemic diseases and cancer is desirable for the development of new drugs and treatment strategies. Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that regulates oxygen homeostasis and plays key roles in a number...

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Detalles Bibliográficos
Autores principales: Kadonosono, Tetsuya, Kuchimaru, Takahiro, Yamada, Shuichi, Takahashi, Yumi, Murakami, Atsushi, Tani, Taeko, Watanabe, Hitomi, Tanaka, Tomoharu, Hirota, Kiichi, Inoue, Masahiro, Tsukamoto, Tetsuya, Toyoda, Takeshi, Urano, Koji, Machida, Kazuhiko, Eto, Tomoo, Ogura, Tomoyuki, Tsutsumi, Hideki, Ito, Mamoru, Hiraoka, Masahiro, Kondoh, Gen, Kizaka-Kondoh, Shinae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213102/
https://www.ncbi.nlm.nih.gov/pubmed/22102864
http://dx.doi.org/10.1371/journal.pone.0026640