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Detection of the Onset of Ischemia and Carcinogenesis by Hypoxia-Inducible Transcription Factor-Based In Vivo Bioluminescence Imaging
An animal model for the early detection of common fatal diseases such as ischemic diseases and cancer is desirable for the development of new drugs and treatment strategies. Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that regulates oxygen homeostasis and plays key roles in a number...
Autores principales: | Kadonosono, Tetsuya, Kuchimaru, Takahiro, Yamada, Shuichi, Takahashi, Yumi, Murakami, Atsushi, Tani, Taeko, Watanabe, Hitomi, Tanaka, Tomoharu, Hirota, Kiichi, Inoue, Masahiro, Tsukamoto, Tetsuya, Toyoda, Takeshi, Urano, Koji, Machida, Kazuhiko, Eto, Tomoo, Ogura, Tomoyuki, Tsutsumi, Hideki, Ito, Mamoru, Hiraoka, Masahiro, Kondoh, Gen, Kizaka-Kondoh, Shinae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213102/ https://www.ncbi.nlm.nih.gov/pubmed/22102864 http://dx.doi.org/10.1371/journal.pone.0026640 |
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