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Combination of suberoylanilide hydroxamic acid with heavy ion therapy shows promising effects in infantile sarcoma cell lines

INTRODUCTION: The pan-HDAC inhibitor (HDACI) suberoylanilide hydroxamic acid (SAHA) has previously shown to be a radio-sensitizer to conventional photon radiotherapy (XRT) in pediatric sarcoma cell lines. Here, we investigate its effect on the response of two sarcoma cell lines and a normal tissue c...

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Detalles Bibliográficos
Autores principales: Oertel, Susanne, Thiemann, Markus, Richter, Karsten, Weber, Klaus-J, Huber, Peter E, Perez, Ramon Lopez, Brons, Stephan, Bischof, Marc, Kulozik, Andreas E, Ehemann, Volker, Debus, Jürgen, Blattmann, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213106/
https://www.ncbi.nlm.nih.gov/pubmed/21933400
http://dx.doi.org/10.1186/1748-717X-6-119