The evolution of pyrimethamine resistant dhfr in Plasmodium falciparum of south-eastern Tanzania: comparing selection under SP alone vs SP+artesunate combination

BACKGROUND: Sulphadoxine-pyrimethamine (SP) resistance is now widespread throughout east and southern Africa and artemisinin compounds in combination with synthetic drugs (ACT) are recommended as replacement treatments by the World Health Organization (WHO). As well as high cure rates, ACT has been...

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Detalles Bibliográficos
Autores principales: Malisa, Allen L, Pearce, Richard J, Mutayoba, Ben M, Abdullah, Salim, Mshinda, Hassan, Kachur, Patrick S, Bloland, Peter, Roper, Cally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213132/
https://www.ncbi.nlm.nih.gov/pubmed/22029848
http://dx.doi.org/10.1186/1475-2875-10-317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213132/
https://www.ncbi.nlm.nih.gov/pubmed/22029848
http://dx.doi.org/10.1186/1475-2875-10-317

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