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Histone H3K56 Acetylation, CAF1, and Rtt106 Coordinate Nucleosome Assembly and Stability of Advancing Replication Forks

Chromatin assembly mutants accumulate recombinogenic DNA damage and are sensitive to genotoxic agents. Here we have analyzed why impairment of the H3K56 acetylation-dependent CAF1 and Rtt106 chromatin assembly pathways, which have redundant roles in H3/H4 deposition during DNA replication, leads to...

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Detalles Bibliográficos
Autores principales: Clemente-Ruiz, Marta, González-Prieto, Román, Prado, Félix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213180/
https://www.ncbi.nlm.nih.gov/pubmed/22102830
http://dx.doi.org/10.1371/journal.pgen.1002376