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Reversible and Noisy Progression towards a Commitment Point Enables Adaptable and Reliable Cellular Decision-Making

Cells must make reliable decisions under fluctuating extracellular conditions, but also be flexible enough to adapt to such changes. How cells reconcile these seemingly contradictory requirements through the dynamics of cellular decision-making is poorly understood. To study this issue we quantitati...

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Detalles Bibliográficos
Autores principales: Kuchina, Anna, Espinar, Lorena, Garcia-Ojalvo, Jordi, Süel, Gürol M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213189/
https://www.ncbi.nlm.nih.gov/pubmed/22102806
http://dx.doi.org/10.1371/journal.pcbi.1002273