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Reversible and Noisy Progression towards a Commitment Point Enables Adaptable and Reliable Cellular Decision-Making
Cells must make reliable decisions under fluctuating extracellular conditions, but also be flexible enough to adapt to such changes. How cells reconcile these seemingly contradictory requirements through the dynamics of cellular decision-making is poorly understood. To study this issue we quantitati...
Autores principales: | Kuchina, Anna, Espinar, Lorena, Garcia-Ojalvo, Jordi, Süel, Gürol M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213189/ https://www.ncbi.nlm.nih.gov/pubmed/22102806 http://dx.doi.org/10.1371/journal.pcbi.1002273 |
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