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A Density-Dependent Switch Drives Stochastic Clustering and Polarization of Signaling Molecules

Positive feedback plays a key role in the ability of signaling molecules to form highly localized clusters in the membrane or cytosol of cells. Such clustering can occur in the absence of localizing mechanisms such as pre-existing spatial cues, diffusional barriers, or molecular cross-linking. What...

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Detalles Bibliográficos
Autores principales: Jilkine, Alexandra, Angenent, Sigurd B., Wu, Lani F., Altschuler, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213192/
https://www.ncbi.nlm.nih.gov/pubmed/22102805
http://dx.doi.org/10.1371/journal.pcbi.1002271