Recent methods for polygenic analysis of genome-wide data implicate an important effect of common variants on cardiovascular disease risk

BACKGROUND: Traditional genome-wide association studies are generally limited in their ability explain a large portion of genetic risk for most common diseases. We sought to use both traditional GWAS methods, as well as more recently developed polygenic genome-wide analysis techniques to identify su...

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Detalles Bibliográficos
Autores principales: Simonson, Matthew A, Wills, Amanda G, Keller, Matthew C, McQueen, Matthew B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213201/
https://www.ncbi.nlm.nih.gov/pubmed/22029572
http://dx.doi.org/10.1186/1471-2350-12-146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213201/
https://www.ncbi.nlm.nih.gov/pubmed/22029572
http://dx.doi.org/10.1186/1471-2350-12-146

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