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Dysfunctional γδ T cells contribute to impaired keratinocyte homeostasis in mouse models of obesity

Skin complications and chronic non-healing wounds are common in obesity, metabolic disease and type 2 diabetes. Epidermal γδ T cells normally produce keratinocyte growth factors, participate in wound repair and are necessary for keratinocyte homeostasis. We have determined that in γδ T cell-deficien...

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Detalles Bibliográficos
Autores principales: Taylor, Kristen R., Costanzo, Anne E., Jameson, Julie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213272/
https://www.ncbi.nlm.nih.gov/pubmed/21833015
http://dx.doi.org/10.1038/jid.2011.241