MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells

The MYCN gene plays a critical role in determining the clinical behavior of neuroblastoma. Although it is known that genomic amplification occurs in high-risk subsets, it remains unclear how MYCN expression is regulated in the pathogenesis of neuroblastomas. Herein, we report that MYCN expression wa...

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Detalles Bibliográficos
Autores principales: Gu, Lubing, Zhang, Hailong, He, Jing, Li, Jiansha, Huang, Mei, Zhou, Muxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213308/
https://www.ncbi.nlm.nih.gov/pubmed/21822304
http://dx.doi.org/10.1038/onc.2011.343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213308/
https://www.ncbi.nlm.nih.gov/pubmed/21822304
http://dx.doi.org/10.1038/onc.2011.343

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