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MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells
The MYCN gene plays a critical role in determining the clinical behavior of neuroblastoma. Although it is known that genomic amplification occurs in high-risk subsets, it remains unclear how MYCN expression is regulated in the pathogenesis of neuroblastomas. Herein, we report that MYCN expression wa...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213308/ https://www.ncbi.nlm.nih.gov/pubmed/21822304 http://dx.doi.org/10.1038/onc.2011.343 |