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Endogenous Histones Function as Alarmins in Sterile Inflammatory Liver Injury Through Toll-like Receptor 9 in Mice

Sterile inflammatory insults are known to activate innate immunity and propagate organ damage through the recognition of extracellular damage-associated molecular pattern (DAMP) molecules. Although DAMPs such as endogenous DNA and nuclear high-mobility group box 1 have been shown to be critical in s...

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Detalles Bibliográficos
Autores principales: Huang, Hai, Evankovich, John, Yan, Wei, Nace, Gary, Zhang, Lemeng, Ross, Mark, Liao, Xinghua, Billiar, Timothy, Xu, Jun, Esmon, Charles T, Tsung, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213322/
https://www.ncbi.nlm.nih.gov/pubmed/21721026
http://dx.doi.org/10.1002/hep.24501