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Reduction of metastasis using a non-volatile buffer

The tumor microenvironment is acidic as a consequence of upregulated glycolysis and poor perfusion and this acidity, in turn, promotes invasion and metastasis. We have recently demonstrated that chronic consumption of sodium bicarbonate increased tumor pH and reduced spontaneous and experimental met...

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Detalles Bibliográficos
Autores principales: Ibrahim Hashim, Arig, Cornnell, Heather H., Coelho Ribeiro, Maria de Lourdes, Abrahams, Dominique, Cunningham, Jessica, Lloyd, Mark, Martinez, Gary V., Gatenby, Robert A., Gillies, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213349/
https://www.ncbi.nlm.nih.gov/pubmed/21861189
http://dx.doi.org/10.1007/s10585-011-9415-7