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Reduction of metastasis using a non-volatile buffer
The tumor microenvironment is acidic as a consequence of upregulated glycolysis and poor perfusion and this acidity, in turn, promotes invasion and metastasis. We have recently demonstrated that chronic consumption of sodium bicarbonate increased tumor pH and reduced spontaneous and experimental met...
Autores principales: | Ibrahim Hashim, Arig, Cornnell, Heather H., Coelho Ribeiro, Maria de Lourdes, Abrahams, Dominique, Cunningham, Jessica, Lloyd, Mark, Martinez, Gary V., Gatenby, Robert A., Gillies, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213349/ https://www.ncbi.nlm.nih.gov/pubmed/21861189 http://dx.doi.org/10.1007/s10585-011-9415-7 |
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